Two-Dimensional Chromatography

Adaptive two-dimensional microgas chromatography.

We proposed and investigated a novel adaptive two-dimensional (2-D) microgas chromatography system, which consists of one 1st-dimensional column, multiple parallel 2nd-dimensional columns, and a decision-making module. The decision-making module, installed between the 1st- and 2nd-dimensional columns, normally comprises an on-column nondestructive vapor detector, a flow routing system, and a co...

QSRR application to two-dimensional gas chromatography

Gas chromatography (GC) and two-dimensional GC (GC-GC) are widely used for separation, structure elucidation and quantitative analysis. In GC and GC-GC, the chemical structure is elucidated by comparing the measured retention time of each compound with the database. But, structure elucidation is infeasible when the retention time is not available from the database. Thus, quantitative structure ...

Quantitative Two-dimensional Thin-layer Chromatography of Naturally Occurring Phospholipids.

Orthogonality of separation in two-dimensional liquid chromatography.

Two-dimensional liquid chromatography is often used to reduce the proteomic sample complexity prior to tandem mass spectrometry analysis. The 2D-LC performance depends on the peak capacity in both chromatographic dimensions, and separation orthogonality. The peak capacity and selectivity of many LC modes for peptides is not well known, and mathematical characterization for orthogonality is unde...

Automated tank for one- or two-dimensional thin-layer chromatography.

An automated one- or two-dimensional TLC tank is described. The solvent front is monitored by a photocell or recycling timers.